Ameliorative effects of operculina turpethum and its isolated stigma-5,22dien-3-o-β-D-glucopyranoside on the hematological parameters of male mice exposed to n-nitrosodimethylamine, a potent carcinogen

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Potential Recovery from Hepatotoxicity by Operculina Turpethum and Its Isolated Stigma-5,22dien-3-o-b-d- Glucopyranoside against N- Nitrosodimethylamine, a Potent Carcinogen in Animal Model

N-Nitrosodimethylamine is one of the main N-nitroso compound,commonly found in drinking water and is a potent hepatotoxin, carcinogen and mutagen. The curative effect of ethanolic root extract of Operculina turpethum was studied for its possible hepatoprotective potential against NNitrosodimethylamine in Swiss albino mice. Hepatic malondialdehyde (MDA), Superoxide dismutase(SOD),catalase(CAT),g...

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Attenuation of N-nitrosodimethylamine induced hepatotoxicity by Operculina turpethum in Swiss Albino mice

  Objective(s): To appraise the antihepatotoxic efficacy of ethanolic extract of Operculum turpethum root on the liver of Swiss albino mice.   Materials and Methods:   Hepatic fibrosis was induced in adult male albino mice through intraperitoneal administrations of N-nitrosodimethylamine (NDMA) at the concentration of 10 mg/kg body weight. The liver toxicity and therapeutic effect of the ...

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Attenuation of N-nitrosodimethylamine induced hepatotoxicity by Operculina turpethum in Swiss Albino mice

OBJECTIVE(S) To appraise the antihepatotoxic efficacy of ethanolic extract of Operculum turpethum root on the liver of Swiss albino mice. MATERIALS AND METHODS Hepatic fibrosis was induced in adult male albino mice through intraperitoneal administrations of N-nitrosodimethylamine (NDMA) at the concentration of 10 mg/kg body weight. The liver toxicity and therapeutic effect of the plant ethano...

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attenuation of n-nitrosodimethylamine induced hepatotoxicity by operculina turpethum in swiss albino mice

objective(s): to appraise the antihepatotoxic efficacy of ethanolic extract of operculum turpethum root on the liver of swiss albino mice.   materials and methods:   hepatic fibrosis was induced in adult male albino mice through intraperitoneal administrations of n-nitrosodimethylamine (ndma) at the concentration of 10 mg/kg body weight. the liver toxicity and therapeutic effect of the plant et...

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the effects of planning on accuracy and complexity of iranian efl students’ written narrative task performance

this study compared the different effects of form-focused guided planning vs. meaning-focused guided planning on iranian pre-intermediate students’ task performance. the study lasted for three weeks and concentrated on eight english structures. forty five pre-intermediate iranian students were randomly assigned to three groups of guided planning focus-on-form group (gpfg), guided planning focus...

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ژورنال

عنوان ژورنال: Toxicology International

سال: 2014

ISSN: 0971-6580

DOI: 10.4103/0971-6580.128789